Now showing items 1-5 of 44

  • An analysis of the transitions between down and up states of the cortical slow oscillation under urethane anaesthesia

    Wilson, Marcus T.; Barry, Melissa; Reynolds, John N.J.; Crump, William P.; Steyn-Ross, D. Alistair; Steyn-Ross, Moira L.; Sleigh, James W. (Springer Netherlands, 2010)
    We study the dynamics of the transition between the low- and high-firing states of the cortical slow oscillation by using intracellular recordings of the membrane potential from cortical neurons of rats. We investigate the ...
  • Anesthesia-induced state transitions in neuronal populations

    Sleigh, James W.; Steyn-Ross, Moira L.; Steyn-Ross, D. Alistair; Voss, Logan J.; Wilson, Marcus T. (Humana Press., 2010)
    It is a simple observation that the function of the central nervous system changes abruptly at certain critical brain concentrations of the anesthetic drug. This can be viewed as analogous to “state transitions” in systems ...
  • The Bispectral Index: A measure of depth of sleep?

    Sleigh, James W.; Andrzejowski, John; Steyn-Ross, D. Alistair; Steyn-Ross, Moira L. (LIPPINCOTT WILLIAMS & WILKINS, 1999)
    How does physiological sleep affect the Bispectral Index (BIS)? We collected electroencephalographic (EEG) data from five subjects during the early part of the night, comparing the changes in the BIS with the conventional ...
  • Changes in frequency of seizure-like events in stimulated cortical slices

    Mason, J.; Voss, Logan J.; Jacobson, Gregory M.; Elbohouty, Maher; Sleigh, James W.; Steyn-Ross, Moira L.; Steyn-Ross, D. Alistair (IEEE Xplore, 2010)
    Epilepsy affects nearly 3 million people in the United States alone. Given the fact that many people suffer from seizures that are intractable to pharmacological intervention, research groups are investigating the use of ...
  • Characteristics of temporal fluctuations in the hyperpolarized state of the cortical slow oscillation

    Wilson, Marcus T.; Barry, Melissa; Reynolds, John N.J.; Hutchison, E.J.W.; Steyn-Ross, D. Alistair (American Physical Society, 2008)
    We present evidence for the hypothesis that transitions between the low- and high-firing states of the cortical slow oscillation correspond to neuronal phase transitions. By analyzing intracellular recordings of the membrane ...

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