Yao, B., Prinsep, M.R., Nicholson, B.K & Gordon, D.P. (2003). The pterocellins: novel bioactive alkaloids from the marine Bryozoan Ptrerocella vesiculosa. Journal of Natural Products, 66, 1074-1077.
Permanent Research Commons link: http://hdl.handle.net/10289/211
Two new alkaloids, pterocellins A and B, have been isolated from the New Zealand marine bryozoan Pterocella vesiculosa. Structural elucidation was achieved through NMR and mass spectral analysis in conjunction with a single-crystal X-ray diffraction study of pterocellin A. The pterocellins possess a novel heterocyclic skeleton and exhibit potent antitumor activity and antimicrobial activity in vitro but only modest activity in the in vivo hollow fiber assay at the National Cancer Institute.
This article is published in the Journal of Natural Products, (c) 2003 American Chemical Society and American Society of Pharmacognosy.