Jacobson, G.M., Voss, L.J., Melin, S.M., Mason, J.P., Cursons, R.T.,…, Sleigh, J.W. (2010). Connexin36 knockout mice display increased sensitivity to pentylenetetrazol-induced seizure-like behaviours. Brain Research, 1360(11), 198-204.
Permanent Research Commons link: http://hdl.handle.net/10289/4613
Large-scale synchronous firing of neurons during seizures is modulated by electrotonic coupling between neurons via gap junctions. To explore roles for connexin36 (Cx36) gap junctions in seizures, we examined the seizure threshold of connexin36 knockout (Cx36KO) mice using a pentylenetetrazol (PTZ) model.
This is an author’s accepted version of an article published in the journal: Brain Research. © 2010 Elsevier.