Jones, M. H., & Scott, J. B. (2014). Scaling of Electrode-Electrolyte Interface Model Parameters In Phosphate Buffered Saline. IEEE Transactions on Biomedical Circuits and Systems, 9(3), 441–448. http://doi.org/10.1109/TBCAS.2014.2333759
Permanent Research Commons link: http://hdl.handle.net/10289/8878
We report how the impedance presented by a platinum electrode scales with the concentration of phosphate buffered saline (PBS). We find that the constant phase element of the model scales with approximately the log of concentration, whereas the resistivity is inversely proportional. Using a novel DC measurement technique we show that the Faradaic response of a platinum electrode, and thus the safe exposure limit, does not scale with concentration below 900mV overpotential across a pair of electrodes. We compare objective measurements made in saline to those made in the spinal cavity of live sheep. We comment upon the appropriateness of using PBS as a substitute for living sheep.
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