Browsing by Supervisor "Lane, Joseph R."
Now showing items 1-11 of 11
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Novel sulfonamides for the treatment of breast and cervical cancers
(The University of Waikato, 2022)A series of novel sulfonamides were studied computationally to identify a potential mechanism of action for the treatment of breast and cervical cancers. Previous in vivo testing demonstrated varying degrees of effectiveness, ... -
A dynamic look into hydrogen bonding In proteins
(The University of Waikato, 2022)This thesis aims to highlight the importance of analysing the dynamic nature of hydrogen bonds and their temporal variation. We also evaluate whether distance alone can and should be used as the main estimator for hydrogen ... -
Studies on the metallacyclic chemistry of thiourea monoanion and dianion ligands; synthesis, structures and theoretical investigations
(The University of Waikato, 2020)This thesis presents studies on the metallacyclic chemistry of thiourea dianion and monoanion ligands. The versatility of thioureas and their relatives (thiosemicarbazones and selenoureas) has been attributed to the ... -
Theoretical study of electronic absorption spectra and photodissociation dynamics of atmospherically relevant molecules
(The University of Waikato, 2019)The absorption of solar radiation by atmospheric species and the corresponding photoinduced processes, define the chemistry of a planet's atmosphere. While many of these photoinduced processes and their effects are well- ... -
An investigation of beryllium coordination chemistry using electrospray ionisation mass spectrometry
(The University of Waikato, 2018)The electrospray ionisation mass spectrometric behaviour of various complexes of beryllium have been investigated in this thesis. These beryllium complexes were prepared in situ on a small scale by preparing appropriate ... -
Understanding the Relative Importance of the Effects of Soluble and Insoluble Inhibitors on the Enzyme Digestibility of Steam Pretreated Radiata Pine
(The University of Waikato, 2018)Lignocellulosic biomass use is one of the keys to growth and development of future biofuels and biochemicals. Amongst the lignocellulosic feedstocks, softwoods are particularly attractive as they have the potential to ... -
Investigating Macromolecular Rate Theory
(The University of Waikato, 2017)Curvature with temperature is a defining characteristic of enzyme catalysed rates. Historically, curvature has been described by Arrhenius behaviour up to a temperature optimum (Tₒₚₜ), while decreases in rates above Tₒₚₜ ... -
An estimation of the concentration of atmospheric nitrous oxide containing complexes
(University of Waikato, 2015)Nitrous oxide (N₂O) is one of the major greenhouse gases responsible for climate change. It also has impacts on the removal of ozone (O₃) from the atmosphere and is now the single most important ozone depleting substance. ... -
Kinetics of Conversion of Dihydroxyacetone to Methylglyoxal in Honey
(University of Waikato, 2015)Mānuka honey contains a unique non-peroxide antibacterial activity which is highly sought after due to the perceived health benefits. Methylglyoxal (MGO) is the compound predominately responsible for this non-peroxide ... -
Isomerism of Complexes Containing Thiourea Dianion Ligands
(University of Waikato, 2014)This thesis reports the synthesis and characterisation of eight new platinum thiourea complexes. Thiourea dianion complexes of the type (Ph₃P)₂PtSC(=NR)NPh, R=Me, Et, Prⁿ, Prⁱ, Buⁿ and (Ph₃P)₂PtSC(=NPh)NR R=Buͭ , p-tol, ... -
Synthesis of Platinum Complexes Containing Bidentate N,O-donor Ligands
(University of Waikato, 2014)The reaction of N,O-donor ligands hippuric acid and N-phenylanthranilic acid with [PtCl₂(COD)] (COD = 1,5-cyclooctadiene) in dichloromethane and in the presence of silver(I) oxide yields the complexes [Pt{OC(O)CH₂N(COPh)}(COD)] ...
