Browsing by Author "Andrews, Emma Sophie Vout"

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  • Crystal structure of an inferred ancestral bacterial pyruvate decarboxylase

    Buddrus, Lisa; Andrews, Emma Sophie Vout; Leak, David J.; Danson, Michael J.; Arcus, Vickery L.; Crennell, Susan J. (International Union of Crystallography, 2018)
    Pyruvate decarboxylase (PDC; EC 4.1.1.1) is a key enzyme in homofermentative metabolism where ethanol is the major product. PDCs are thiamine pyrophos­phate- and Mg2+ ion-dependent enzymes that catalyse the non-oxidative ...

  • Crystal structure of pyruvate decarboxylase from Zymobacter palmae

    Buddrus, Lisa; Andrews, Emma Sophie Vout; Leak, David J.; Danson, Michael J.; Arcus, Vickery L.; Crennell, Susan J. (International Union of Crystallography, 2016)
    Pyruvate decarboxylase (PDC; EC 4.1.1.1) is a thiamine pyrophosphate- and Mg²⁺ ion-dependent enzyme that catalyses the non-oxidative decarboxylation of pyruvate to acetaldehyde and carbon dioxide. It is rare in bacteria, ...

  • Post-transcriptional modulation of the SigF regulon inMycobacterium smegmatisby the PhoH2 toxin-antitoxin

    Andrews, Emma Sophie Vout; Rzoska-Smith, Elizabeth; Arcus, Vickery L. (Public Library Science, 2020)
    PhoH2 proteins are highly conserved across bacteria and archaea yet their biological function is poorly characterised. We examined the growth profiles of Mycobacterium smegmatis strains mc²155 and mc²155 ΔphoH2 and observed ...

  • The Biology and Biochemistry of PhoH2 proteins

    Andrews, Emma Sophie Vout (University of Waikato, 2013)
    PhoH2 proteins are found in a diverse range of organisms. To date little is known about these proteins and the role they play in the organisms in which they reside. PhoH2 is a PIN PhoH domain fusion, and these proteins are ...

Co-authors for Emma Sophie Vout Andrews

Emma Sophie Vout Andrews has 6 co-authors in Research Commons.

Supervised by Emma Sophie Vout Andrews

Showing up to 5 theses - most recently added to Research Commons first.

  • Do PhoH2 proteins regulate SigF in mycobacteria?

    Rzoska-Smith, Elizabeth (The University of Waikato, 2018)
    There is little known about the role of the PhoH2 proteins in biology. PhoH2 consists of two domains, an N-terminal PIN domain with RNase activity and a C-terminal PhoH domain shown to have ATP induced RNA helicase activity. ...

  • Evolution of Bacillus subtilis: A Novel Phenotype and its Challenges

    Murray, Mitchell John (The University of Waikato, 2018)
    The enzyme LeuB from the last common ancestor of the firmicutes has been statistically recreated using several different methods. This project deals with two versions, Rec/LG and Rec/EX. To better understand these resurrected ...

  • Caldalkalibacillus thermarum PhoH2: Solving the solubility puzzle

    Dillon, Brooke Jane (University of Waikato, 2017)
    Previous attempts to determine the structure of the protein PhoH2 from Mycobacterium tuberculosis, Mycobacterium smegmatis and Thermobispora bispora have been unsuccessful producing diffraction data to low resolution. The ...