Browsing by Author "Beretta, Lorenzo"
Now showing items 1-3 of 3
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A 3-factor epistatic model predicts digital ulcers in Italian scleroderma patients
(Elsevier, 2010)Background The genetic background may predispose systemic sclerosis (SSc) patients to the development of digital ulcers (DUs). Methods Twenty-two functional cytokine single nucleotide polymorphisms (SNPs) and 3 HLA class ... -
Evolving concurrent Petri net models of epistasis
(Springer, 2010)A genetic algorithm is used to learn a non-deterministic Petri netbased model of non-linear gene interactions, or statistical epistasis. Petri nets are computational models of concurrent processes. However, often certain ... -
Modelling epistasis in genetic disease using Petri nets, evolutionary computation and frequent itemset mining
(Elsevier, 2010)Petri nets are useful for mathematically modelling disease-causing genetic epistasis. A Petri net model of an interaction has the potential to lead to biological insight into the cause of a genetic disease. However, defining ...
