Browsing by Author "Denny, William A."

Now showing items 1-2 of 2

  • 2-(1,4-Dioxo-1,4-dihydro-2-naphthyl)-2-methylpropanoic acid

    Dempster-Rivett, Kieran J.; Main, Lyndsay; Nicholson, Brian K.; Denny, William A. (Blackwell Munksgaard, 2007)
    The sterically crowded title compound, C₁₄H₁₂O₄, crystallizes as centrosymmetric hydrogen-bonded dimers involving the carboxyl groups. The naphthoquinone ring system is folded by 11.5 (1)° about a vector joining the 1,4-C ...
  • Transcriptional changes in response to ketamine ester-analogs SN 35210 and SN 35563 in the rat brain

    Jacobson, Gregory M.; Voss, Logan J.; Klockars, Anica; Bird, Steve; Dimitrov, Ivo; Denny, William A.; Olszewski, Pawel K.; Sleigh, James W.; Harvey, Martyn G. (BMC, 2019)
    Background Ketamine ester analogs, SN 35210 and SN 35563, demonstrate different pharmacological profiles to ketamine in animal models. Both confer hypnosis with predictably rapid offset yet, paradoxically, SN35563 induces ...