Now showing items 1-2 of 2

  • Determination of ribonuclease sequence-specificity using Pentaprobes and mass spectrometry

    McKenzie, Joanna Leigh; Duyvestyn, Johanna Maria; Smith, Tony C.; Bendak, Katerina; Mackay, Joel P.; Cursons, Raymond T.; Cook, Gregory M.; Arcus, Vickery L. (RNA Society, 2012)
    The VapBC toxin-antitoxin (TA) family is the largest of nine identified TA families. The toxin, VapC, is a metal-dependent ribonuclease that is inhibited by its cognate antitoxin, VapB. Although the VapBCs are the largest ...
  • Mechanism of RNase cleavage by VapC from Pyrobaculum aerophilum

    Duyvestyn, Johanna Maria (University of Waikato, 2012)
    Proteins belonging to the PIN-domain family are widespread across bacteria, archaea and eukaryotes. PIN-domain structures are well characterised and contain three highly conserved acidic residues that are orientated to ...