Browsing by Author "Hobbs, Joanne K."

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Change in heat capacity for enzyme catalysis determines temperature dependence of enzyme catalyzed ratesnzyme Catalyzed Rates

Hobbs, Joanne K.; Jiao, Wanting; Easter, Ashley Davys; Parker, Emily J.; Schipper, Louis A.; Arcus, Vickery L. (American Chemical Society, 2013)

The increase in enzymatic rates with temperature up to an optimum temperature (Topt) is widely attributed to classical Arrhenius behavior, with the decrease in enzymatic rates above Topt ascribed to protein denaturation ...
On the origin and evolution of thermophily: Reconstruction of functional precambrian enzymes from ancestors of Bacillus

Hobbs, Joanne K.; Shepherd, Caris; Saul, David; Demetras, Nicholas J.; Haaning, Svend; Monk, Colin R.; Daniel, Roy M.; Arcus, Vickery L. (Oxford University Press, 2011)

Thermophily is thought to be a primitive trait, characteristic of early forms of life on Earth, that has been gradually lost over evolutionary time. The genus Bacillus provides an ideal model for studying the evolution of ...

Joanne K. Hobbs has 11 co-authors in Research Commons.

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The evolution of AroA and MurA enzymes from Bacillus

Oulavallickal, Tifany (University of Waikato, 2016)

MurA and AroA are important antibacterial targets due to their essentiality in microorganisms and the absence of their respective pathways within mammals. Although much research has focussed on these enzymes, little is ...

Co-authors for Joanne K. Hobbs