Browsing by Author "Jacobson, Gregory M."
Now showing items 1-5 of 18
-
Association of innate immune single-nucleotide polymorphisms with the electroencephalogram during desflurane general anaesthesia
(Springer, 2013)The electroencephalogram (EEG) records the electrical activity of the brain and enables effects of anaesthetic drugs on brain functioning to be monitored. Identification of genes contributing to EEG variability during ... -
Changes in frequency of seizure-like events in stimulated cortical slices
(IEEE Xplore, 2010)Epilepsy affects nearly 3 million people in the United States alone. Given the fact that many people suffer from seizures that are intractable to pharmacological intervention, research groups are investigating the use of ... -
Clonal cell proliferation in the mammary gland
(The University of Waikato, 2004)The primary aim of this thesis was to classify the nature of the clonal expansion of cells that gives rise to bovine and murine mammary epithelia. It is generally assumed that the mammary gland is derived from the outgrowth ... -
Connexin36 knockout mice display increased sensitivity to pentylenetetrazol-induced seizure-like behaviors
(Elsevier, 2010)Large-scale synchronous firing of neurons during seizures is modulated by electrotonic coupling between neurons via gap junctions. To explore roles for connexin36 (Cx36) gap junctions in seizures, we examined the seizure ... -
Development of a qPCR method to measure mitochondrial and genomic DNA damage with application to chemotherapy-induced DNA damage and cryopreserved cells
(MDPI AG, 2016)DNA damage quantitation assays such as the comet assay have focused on the measurement of total nuclear damage per cell. The adoption of PCR-based techniques to quantify DNA damage has enabled sequence- and organelle-specific ...
