Browsing by Author "Kallingappa, Prasanna Kumar"

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Quiescence induces epigenetic changes in bovine fibroblasts and improves their reprogramming into cloned embryos

Kallingappa, Prasanna Kumar (University of Waikato, 2013)

Cloning by somatic cell nuclear transfer (SCNT) forces cells to lose their lineage-specific epigenetic marks and become totipotent again. This reprogramming process often results in epigenetic and transcriptional aberrations ...