Browsing by Author "Larsen, Kristofer"

Now showing items 1-2 of 2

  • Isolation and identification of a cis-C₈-diol-ester of okadaic acid from Dinophysis acuta in New Zealand

    Miles, Christopher O.; Wilkins, Alistair L.; Hawkes, Allan D.; Jensen, Dwayne J.; Cooney, Janine M.; Larsen, Kristofer; Petersen, Dirk; Rise, Frode; Beuzenberg, Veronica; Lincoln MacKenzie, A. (Elsevier, 2006)
    A cis-isomer of a C8-diol ester of okadaic acid (1) was isolated during large-scale purification of pectenotoxins (PTXs) from extracts of Dinophysis acuta collected from the west coast of South Island, New Zealand. The ...
  • A structural basis for the reduced toxicity of dinophysistoxin-2

    Huhn, Jason; Jeffrey, Philip D.; Larsen, Kristofer; Rundberget, Thomas; Rise, Frode; Cox, Neil R.; Arcus, Vickery L.; Shi, Yigong; Miles, Christopher O. (American Chemical Society, 2009)
    Okadaic acid (OA), dinophysistoxin-1 (DTX-1), and dinophysistoxin-2 (DTX-2) are algal toxins that can accumulate in shellfish and cause diarrhetic shellfish poisoning. Recent studies indicate that DTX-2 is about half as ...