Browsing by Author "Leak, David J."

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  • Crystal structure of an inferred ancestral bacterial pyruvate decarboxylase

    Buddrus, Lisa; Andrews, Emma Sophie Vout; Leak, David J.; Danson, Michael J.; Arcus, Vickery L.; Crennell, Susan J. (International Union of Crystallography, 2018)
    Pyruvate decarboxylase (PDC; EC 4.1.1.1) is a key enzyme in homofermentative metabolism where ethanol is the major product. PDCs are thiamine pyrophos­phate- and Mg2+ ion-dependent enzymes that catalyse the non-oxidative ...

  • Crystal structure of pyruvate decarboxylase from Zymobacter palmae

    Buddrus, Lisa; Andrews, Emma Sophie Vout; Leak, David J.; Danson, Michael J.; Arcus, Vickery L.; Crennell, Susan J. (International Union of Crystallography, 2016)
    Pyruvate decarboxylase (PDC; EC 4.1.1.1) is a thiamine pyrophosphate- and Mg²⁺ ion-dependent enzyme that catalyses the non-oxidative decarboxylation of pyruvate to acetaldehyde and carbon dioxide. It is rare in bacteria, ...

Co-authors for David J. Leak

David J. Leak has 5 co-authors in Research Commons.