Browsing by Author "Olszewski, Pawel K."

Now showing items 1-5 of 10

  • Adhesion GPCRs are widely expressed throughout the subsections of the gastrointestinal tract

    Badiali, Luca; Cedernaes, Jonathan; Olszewski, Pawel K.; Nylander, Olof; Vergoni, Anna V.; Schiöth, Helgi B. (BioMed Central Ltd, 2012)
    Background: G protein-coupled receptors (GPCRs) represent one of the largest families of transmembrane receptors and the most common drug target. The Adhesion subfamily is the second largest one of GPCRs and its several ...
  • Central oxytocin and food intake: focus on macronutrient-driven reward

    Klockars, Anica; Levine, Allen S.; Olszewski, Pawel K. (FRONTIERS MEDIA SA, 2015)
    Centrally acting oxytocin (OT) is known to terminate food consumption in response to excessive stomach distension, increase in salt loading, and presence of toxins. Hypothalamic-hindbrain OT pathways facilitate these aspects ...
  • Effect of oxytocin on hunger discrimination

    Head, Mitchell Antony; Jewett, David C.; Gartner, Sarah N.; Klockars, Anica; Levine, Allen S.; Olszewski, Pawel K. (Frontiers Media SA, 2019)
    Centrally and peripherally administered oxytocin (OT) decreases food intake and activation of the endogenous OT systems, which is associated with termination of feeding. Evidence gathered thus far points to OT as a facilitator ...
  • Feed-forward mechanisms: Addiction-like behavioral and molecular adaptations in overeating

    Alsiö, Johan; Olszewski, Pawel K.; Levine, Allen S.; Schiöth, Helgi B. (Elsevier, 2012)
    Food reward, not hunger, is the main driving force behind eating in the modern obesogenic environment. Palatable foods, generally calorie-dense and rich in sugar/fat, are thus readily overconsumed despite the resulting ...
  • Intragastric preloads of L-tryptophan reduce ingestive behavior via oxytocinergic neural mechanisms in male mice

    Gartner, Sarah Nicole; Aidney, Fraser; Klockars, Anica; Prosser, Colin G.; Carpenter, Elizabeth A.; Isgrove, Kiriana; Levine, Allen S.; Olszewski, Pawel K. (Elsevier, 2018)
    Human and laboratory animal studies suggest that dietary supplementation of a free essential amino acid, l-tryptophan (TRP), reduces food intake. It is unclear whether an acute gastric preload of TRP decreases consumption ...

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