Browsing by Author "Schiöth, Helgi B."
Now showing items 1-4 of 4
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Adhesion GPCRs are widely expressed throughout the subsections of the gastrointestinal tract
(BioMed Central Ltd, 2012)Background: G protein-coupled receptors (GPCRs) represent one of the largest families of transmembrane receptors and the most common drug target. The Adhesion subfamily is the second largest one of GPCRs and its several ... -
Feed-forward mechanisms: Addiction-like behavioral and molecular adaptations in overeating
(Elsevier, 2012)Food reward, not hunger, is the main driving force behind eating in the modern obesogenic environment. Palatable foods, generally calorie-dense and rich in sugar/fat, are thus readily overconsumed despite the resulting ... -
Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans
(Public Library of Science, 2012)Neurobeachin (Nbea) regulates neuronal membrane protein trafficking and is required for the development and functioning of central and neuromuscular synapses. In homozygous knockout (KO) mice, Nbea deficiency causes perinatal ... -
The orphan G protein-coupled receptor gene GPR178 is evolutionary conserved and altered in response to acute changes in food intake
(Public Library of Science, 2015-06-05)G protein-coupled receptors (GPCRs) are a class of integral membrane proteins mediating physiological functions fundamental for survival, including energy homeostasis. A few years ago, an amino acid sequence of a novel ...
