Browsing by Author "Tehei, Moeava"
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Dynamics of immobilized and native Escherichia coli dihydrofolate reductase by quasielastic neutron scattering
Tehei, Moeava; Smith, Jeremy C.; Monk, Colin R.; Ollivier, Jacques; Oettl, Martin; Kurkal, Vandana; Finney, John L.; Daniel, Roy M. (Biophysical Society, 2006-10)The internal dynamics of native and immobilized Escherichia coli dihydrofolate reductase (DHFR) have been examined using incoherent quasielastic neutron scattering. These results reveal no difference between the high ... -
Enzyme activity and flexibility at very low hydration
Kurkal, Vandana; Daniel, Roy M.; Finney, John L.; Tehei, Moeava; Dunn, Rachel V.; Smith, Jeremy C. (Biophysical Society, 2005-05)Recent measurements have demonstrated enzyme activity at hydrations as low as 3%. This raises the question of whether hydration-induced enzyme flexibility is important for activity. Here, to address this, picosecond dynamic ... -
Protein dynamics and stability: The distribution of atomic fluctuations in thermophilic and mesophilic dihydrofolate reductase derived using elastic incoherent neutron scattering
Meinhold, Lars; Clement, David; Tehei, Moeava; Daniel, Roy M.; Finney, John L.; Smith, Jeremy C. (Biophysical Society, 2008-02)The temperature dependence of the dynamics of mesophilic and thermophilic dihydrofolate reductase is examined using elastic incoherent neutron scattering. It is demonstrated that the distribution of atomic displacement ... -
Review: Fundamental and biotechnological applications of neutron scattering measurements for macromolecular dynamics
Tehei, Moeava; Daniel, Roy M.; Zaccai, Giuseppe (Springer, 2006)To explore macromolecular dynamics on the picosecond timescale, we used neutron spectroscopy. First, molecular dynamics were analyzed for the hyperthermophile malate dehydrogenase from Methanococcus jannaschii and a ...
Co-authors for Moeava Tehei
Moeava Tehei has 11 co-authors in Research Commons.