Browsing by Author "Tehei, Moeava"
Now showing items 1-4 of 4
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Dynamics of immobilized and native Escherichia coli dihydrofolate reductase by quasielastic neutron scattering
(Biophysical Society, 2006-10)The internal dynamics of native and immobilized Escherichia coli dihydrofolate reductase (DHFR) have been examined using incoherent quasielastic neutron scattering. These results reveal no difference between the high ... -
Enzyme activity and flexibility at very low hydration
(Biophysical Society, 2005-05)Recent measurements have demonstrated enzyme activity at hydrations as low as 3%. This raises the question of whether hydration-induced enzyme flexibility is important for activity. Here, to address this, picosecond dynamic ... -
Protein dynamics and stability: The distribution of atomic fluctuations in thermophilic and mesophilic dihydrofolate reductase derived using elastic incoherent neutron scattering
(Biophysical Society, 2008-02)The temperature dependence of the dynamics of mesophilic and thermophilic dihydrofolate reductase is examined using elastic incoherent neutron scattering. It is demonstrated that the distribution of atomic displacement ... -
Review: Fundamental and biotechnological applications of neutron scattering measurements for macromolecular dynamics
(Springer, 2006)To explore macromolecular dynamics on the picosecond timescale, we used neutron spectroscopy. First, molecular dynamics were analyzed for the hyperthermophile malate dehydrogenase from Methanococcus jannaschii and a ...
