Browsing by Author "van Ginkel, Roel"

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  • Isolation, Structural Determination and Acute Toxicity of Pinnatoxins E, F and G

    Selwood, Andrew I.; Miles, Christopher O.; Wilkins, Alistair L.; van Ginkel, Roel; Munday, Rex; Rise, Frode; McNabb, Paul (American Chemical Society, 2010)
    Pinnatoxins and pteriatoxins are a group of cyclic imine toxins that have hitherto only been isolated from Japanese shellfish. As with other cyclic imine shellfish toxins, pinnatoxins cause rapid death in the mouse bioassay ...
  • Semisynthesis of S-Desoxybrevetoxin-B2 and Brevetoxin-B2, and Assessment of Their Acute Toxicities

    Selwood, Andrew I.; van Ginkel, Roel; Wilkins, Alistair L.; Munday, Rex; Ramsdell, John S.; Jensen, Dwayne J.; Cooney, Janine M.; Miles, Christopher O. (American Chemical Society, 2008)
    animals and people consuming seafood. Brevetoxin-B2 (5) is a toxic metabolite produced in shellfish exposed to algae that contain brevetoxin-B (1). S-Desoxybrevetoxin-B2 (4) has been proposed as a cometabolite produced ...