Now showing items 1-3 of 3

  • Caldalkalibacillus thermarum PhoH2: Solving the solubility puzzle

    Dillon, Brooke Jane (University of Waikato, 2017)
    Previous attempts to determine the structure of the protein PhoH2 from Mycobacterium tuberculosis, Mycobacterium smegmatis and Thermobispora bispora have been unsuccessful producing diffraction data to low resolution. The ...
  • Do PhoH2 proteins regulate SigF in mycobacteria?

    Rzoska-Smith, Elizabeth (The University of Waikato, 2018)
    There is little known about the role of the PhoH2 proteins in biology. PhoH2 consists of two domains, an N-terminal PIN domain with RNase activity and a C-terminal PhoH domain shown to have ATP induced RNA helicase activity. ...
  • Evolution of Bacillus subtilis: A Novel Phenotype and its Challenges

    Murray, Mitchell John (The University of Waikato, 2018)
    The enzyme LeuB from the last common ancestor of the firmicutes has been statistically recreated using several different methods. This project deals with two versions, Rec/LG and Rec/EX. To better understand these resurrected ...