Browsing by Supervisor "Cursons, Raymond T."
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A Comparative Analysis of Equine Mesenchymal Stromal Cells and Dermal Fibroblasts
(The University of Waikato, 2017)The aim of this study was to isolate and characterise equine mesenchymal stromal cells from various sources and to compare their biological properties to that of dermal fibroblasts. By using multiple conventional methods ... -
A Comparison of Equine Adipose Tissue, Bone Marrow and Peripheral Blood as Sources of Mesenchymal Stem Cells
(University of Waikato, 2014)Lameness is a significant cause of wastage in equine athletes, with reportedly 66% days lost from training being contributed to musculoskeletal injuries. The use of regenerative cell therapies has been suggested as an ... -
The Association of Outer Ear Commensal Bacteria with Otitis Media in Children
(University of Waikato, 2012)Background: Middle ear infections (otitis media) are a significant burden on children’s health. They are one of the more common childhood ailments and are responsible for about a third of children’s general practitioner ... -
Bovine Pre-gastrulation Development and the role Of Rauber's Layer
(University of Waikato, 2016)Although conception rates in cattle are estimated to be 90%, little over half of each insemination results in the birth of offspring. The majority of total combined foetal and embryonic loss is sustained between the bovine ... -
Comparative safety, pharmacokinetic and pharmacodynamic evaluation of three oral selenium compounds in cancer patients
(The University of Waikato, 2019)Selenium (Se) is an essential trace element involved in many biological processes in humans. Se compounds have demonstrated growth inhibition of malignant cells and tumours in many experimental models. Furthermore, combining ... -
Cracking the resistance of non-tuberculosis mycobacterium against existing antibiotics
(University of Waikato, 2015)Mycobacterium avium (M. avium) is quickly becoming the most prevalent Mycobacterium infection in western countries. M. avium is an opportunistic pulmonary pathogen, infecting patients who often are vulnerable due to existing ... -
Detection of somatic mutations in EGFR and KRAS genes in formalin-fixed paraffin-embedded specimens from Non-Small Cell Lung Cancer Patients
(University of Waikato, 2012)Non-small-cell lung cancer (NSCLC) accounts for 80% of lung cancer and has a 5 year survival rate of just 15%. Recently, tyrosine kinase inhibitors (TKIs) have been found to give dramatic therapeutic benefit to some patients ... -
Detection of Toxoplasma Gondii in Fresh New Zealand Farmed Meat by the Polymerase Chain Reaction
(University of Waikato, 2015)Toxoplasma gondii is an obligate intracellular parasite that is estimated to infect one third of the world’s human population. Upon infection this parasite causes the disease toxoplasmosis which in most healthy humans is ... -
The DNA Binding Protein Lsr2 from Mycobacterium tuberculosis
(University of Waikato, 2012)Lsr2 is a small, basic DNA binding protein that is highly conserved in mycobacteria and related actinomycetes. Lsr2 is essential for growth in Mycobacterium tuberculosis and previous studies have shown that Lsr2 is involved ... -
Effect of Body Condition Score at Calving on Adaptive Immune Function During Early Lactation in New Zealand Dairy Cows: Effect of calving body condition on adaptive immune function
(University of Waikato, 2014)The extent of postpartum negative energy balance in dairy cows is positively associated with body condition score (BCS) at calving. Results of epidemiological studies have indicated that calving BCS is positively correlated ... -
The Effects of Different Cryoprotectants on Stallion Epididymal Spermatozoa
(University of Waikato, 2011)Any event that makes semen collection or mating impossible, such as death, castration, or injury, may terminate a stallion’s breeding career. Fortunately, stallion sperm which are capable of fertilization can be harvested ... -
Honey as an antiviral agent against respiratory syncytial virus
(University of Waikato, 2011)Respiratory syncytial virus is the most frequent cause of hospitalization for viral respiratory infections in infants and young children worldwide. It also severely affects immunocompromised adults and the elderly, however, ... -
How Nutritional and Genetic Factors affect New Zealand Goat Milk Composition
(University of Waikato, 2012)Demand for goat milk produced in New Zealand (NZ) is rapidly growing, particularly in expanding Asian markets. The aim of this study was to investigate how genetic and nutritional factors influence milk composition of NZ ... -
The Identification, Isolation and Partial Characterisation of VapA-encoding virulence plasmids in Rhodococcus equi found in New Zealand.
(The University of Waikato, 2010)This thesis describes the identification, isolation and partial characterisation of VapA-encoded virulence plasmids present in Rhodococcus equi (R. equi) found in foals in New Zealand. R. equi infection associated with the ... -
Investigating molecular approaches for detection of pathogens in horses
(The University of Waikato, 2018)Infectious disease of equines has significant impacts on the New Zealand equine industry, causing avoidable morbidity and mortality. The correct identification of the aetiological agents involved in such infections allows ... -
Investigating the Anti-inflammatory Activity of Honey
(University of Waikato, 2012)Honey has various bioactivities with health-benefiting properties. It has been registered for use in wound dressings but before it can be registered with regulatory authorities for sale with claims for therapeutic actions ... -
Molecular Studies of House Mice in Southern New Zealand
(University of Waikato, 2011)The house mouse, Mus Musculus, was first introduced into New Zealand in significant numbers in the mid nineteenth century. Earlier research suggests that multiple introductions of the three subspecies of house mouse M. m. ... -
Mycobacterium tuberculosis strains in New Zealand: phylogeny and structural biology
(The University of Waikato, 2019)Mycobacterium tuberculosis is an obligate human pathogen and is the primary causative agent of tuberculosis. New Zealand has a relatively low incidence of tuberculosis disease, however, Māori (the indigenous people of New ... -
Selenium as a Modulator of Efficacy and Toxicity of Chemotherapy and Radiation
(University of Waikato, 2011)Selenium (Se) is an essential trace mineral required in maintaining health in humans. Recent research has demonstrated that Se shows promise as an agent that can reduce the harmful side-effects of chemotherapy (CT) and ... -
Single nucleotide polymorphisms associated with the human electroencephalogram during desflurane anaesthesia
(University of Waikato, 2012)General anaesthesia is an induced state that enables a person to endure surgical procedures without pain or recollection. There is substantial individual variability in the response to anaesthesia and in order to avoid ...
