Browsing by Supervisor "Main, Associate Professor Lyndsay"

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  • pH-sensitive Anticancer Model Prodrug: Amide of Kemp's Acid

    Brooks, Robert Turongo (The University of Waikato, 2009)
    Solid tumours are characterised by lower extracellular pH (as low as 5.8 pH) compared to normal healthy cellular pH (actively regulated at pH 7.3). This difference may be exploited with an acid-sensitive anti-tumour prodrug ...