Browsing by Supervisor "Peters, Linda"
Now showing items 1-10 of 10
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Characterisation of VMO1 in Human Tissues
(University of Waikato, 2014)The Vitelline membrane outer layer protein 1 (VMO1) was first identified in the Vitelline membrane of the chicken egg. This membrane almost entirely protein that separates the egg white from the yolk in amniotic eggs ... -
Detection of Toxoplasma Gondii in Fresh New Zealand Farmed Meat by the Polymerase Chain Reaction
(University of Waikato, 2015)Toxoplasma gondii is an obligate intracellular parasite that is estimated to infect one third of the world’s human population. Upon infection this parasite causes the disease toxoplasmosis which in most healthy humans is ... -
Differential effects of organic versus inorganic selenium species on BRCA1-mutated and non-mutated breast cancer cell lines
(University of Waikato, 2016)Selenium (Se) is an important trace element required for maintaining human health. Small amounts of Se has a chemoprotective effect to protect cells from oxidative damage, but higher dosages can introduce damage to DNA, ... -
Doxycycline-inducible overexpression of NANOG in bovine fibroblasts and nuclear transfer embryos
(University of Waikato, 2015)Naïve pluripotent embryonic stem cells (ES cells) have the ability to give rise to all cell types including functional gametes. These cells have been well established in mice and rats. The potential for biomedical and ... -
Expression and Purification of Recombinant VMO1 Protein
(University of Waikato, 2015)Hearing loss is a common sensory deficit that affects more than 275 million people worldwide. Identifying and understanding the genetic causes which underlie hearing loss can lead to improved diagnostic and treatment ... -
General Anaesthetic Modulation of Memory-Related Gene Expression in the Cerebral Cortex
(University of Waikato, 2015)General anaesthetics have been widely used in a clinical setting, having remained one of the most important drugs in medicine for their role in enabling major surgical procedures to be carried out. One of the fundamental ... -
General Anaesthetic Modulation of Memory-Related Gene Expression Using an In vitro Brain Slice Model
(University of Waikato, 2016)General anaesthetics cause widespread neurochemical and physiological changes in the brain. However, the precise mechanism of amnesic action is largely unknown. Gene expression changes in the hippocampus have been a focal ... -
In vitro Effects of Selenium on DNA Damage in BRCA1 Cell Lines
(University of Waikato, 2015)Cancer of the breast is the most common cancer affecting women, with a 1 in 9 lifetime risk of developing breast cancer. Carriers of mutations in the breast cancer susceptibility gene, BRCA1, present with an increased ... -
MicroRNA-mediated silencing of bovine NANOG and MBD3
(University of Waikato, 2015)Embryonic stem cells (ESCs) are pluripotent due to their ability to differentiate into any cell type of the body, including functional gametes. These cells are also capable of infinite self-renewal and are highly receptive ... -
Using putative bovine embryonic stem cell-like cells for nuclear transfer cloning to determine their functional potential
(University of Waikato, 2015)The potential for cloning to improve dissemination of elite genetics has been a goal of livestock scientists for many years. However, efficiency of this technique has remained low compared to other in vitro embryo production ...
