Browsing by Supervisor "Prinsep, Michèle R."
Now showing items 1-10 of 10
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Chemical ecological insights into metabolites of the New Zealand marine sponge, Cliona celata
(University of Waikato, 2015)Marine sponges are known to produce secondary metabolites that have roles including chemical defence against cellular challenge. An investigation into Cliona celata around the Bay of Plenty (New Zealand) was conducted in ... -
Elucidating the Modes of Action of the Antitumour New Zealand Marine Natural Product Pterocellin A
(University of Waikato, 2015)Pterocellin A is a novel bioactive alkaloid isolated from the New Zealand marine bryozoan Pterocella vesiculosa. It exhibits potent antitumour activity towards the P388 (murine leukaemia) cell line in vitro with an IC₅₀ ... -
Identifying iron-binding antioxidants in New Zealand honeydew honey
(University of Waikato, 2013)Iron is an essential element for human physiological function. However, excess free iron could participate in the formation of reactive oxygen species via the Fenton reaction and is thought to be the primary mechanism for ... -
Indole diterpenoid secondary metabolites produced by the Epichloë festucae var. lolii – Lolium perenne symbiosis.
(The University of Waikato, 2019)The indole diterpenoid intermediates of lolitrems in a crude extract of Lolium perenne (L. perenne) seed infected with Epichloë festucae var. lolii (E. festucae var. lolii) and their biological activity against porina ... -
Investigation of Microcystin Processing, Production and Export by Microcystis sp.
(University of Waikato, 2014)During this study, the effect of different processing methods on the microcystin quota (microcystins per cell) was investigated. Microcystins from two Microcystis strains and one Planktothrix strain were quantified using ... -
Investigations of Natural Products from Bryozoa Inhabiting Aotearoa New Zealand
(University of Waikato, 2012)Two species of bryozoa, Pterocella vesiculosa and Plumatella repens, were investigated in an endeavour to isolate and characterise novel secondary metabolites. Analysis of fractions derived from chromatography of a ... -
Isolation and Characterisation of Aeruginosin and Microviridin variants from Microcystis species CAWBG11
(University of Waikato, 2014)The cyanobacterial strain Microcystis species CAWBG11 was investigated in order to isolate and characterise bioactive oligopeptides such as aeruginosins and microviridins. Liquid Chromatography tandem Mass Spectrometry ... -
Natural Product Analysis of Coastal Marine Species of New Zealand
(University of Waikato, 2013)A chemical survey of 58 marine samples obtained from three sites around Tauranga New Zealand was undertaken in an effort to identify new metabolites. MTT assays using HeLa and P388 cell lines were carried out to determine ... -
Novel Brominated Alkaloids from the Bryozoan Amathia citrina
(University of Waikato, 2017)Sixteen bryozoan species from the United Kingdom and New Zealand were surveyed for the presence of brominated secondary metabolites by Liquid Chromatography tandem Mass Spectrometry (LCMS) analysis. Brominated metabolites ... -
Spectroscopic Investigations of Oligopeptides from Aquatic Cyanobacteria: Characterisation of New Oligopeptides, Development of Microcystin Quantification Tools and Investigations into Microcystin Production
(University of Waikato, 2013)Cyanobacteria (blue-green algae) are a group of ancient prokaryotic organisms which have become synonymous with water quality deterioration. An array of compounds is produced by aquatic cyanobacteria, the largest group ...
