Browsing by Supervisor "Wilkins, Dick"
Now showing items 1-9 of 9
-
A promoter characterisation of the Ets transcription factor gene, Ese-2/Elf-5
(The University of Waikato, 2002)E26 transformation specific (Ets) proteins are a versatile class of transcription factors. They act both up and downstream of signal transduction cascades, are causative in cancer generation and are able to control the ... -
Alternative expression forms of the bovine αₛ₁-casein gene
(The University of Waikato, 1999)The αₛ₁-casein A variant protein results from a rare polymorphism in the bovine αₛ₁-casein gene. It is dramatically different from other αₛ₁-caseins in that it has a 13 amino acid (encoded by the entire exon 4 of the ... -
Cationic liposome-mediated transfection of mammary epithelial cells with AAV-based plasmid DNA
(The University of Waikato, 2001)Cationic liposome-mediated delivery of adeno-associated virus (AAV) based plasmid DNA has potential for efficient and safe delivery of DNA into a number of different cell types. The objective of this thesis was to develop ... -
Clonal cell proliferation in the mammary gland
(The University of Waikato, 2004)The primary aim of this thesis was to classify the nature of the clonal expansion of cells that gives rise to bovine and murine mammary epithelia. It is generally assumed that the mammary gland is derived from the outgrowth ... -
Enhanced targeting of triplex forming oligonucleotides
(The University of Waikato, 1999)Oligonucleotides offer the potential to inhibit the expression of specific genes within living cells by binding to the major groove of the DNA helix in a sequence-specific manner to form a DNA triple helix. The ultimate ... -
Gene expression underlying ferret hair growth initiation induced by melatonin and modified by steroids
(The University of Waikato, 2001)Synchronised ferret winter pelage development induced by melatonin was utilised as an in vivo model for studying gene expression associated with the hair growth cycle. The effects of melatonin and steroids on hair follicle ... -
Prolactin-induced proteins and dependence on protein synthesis for β-casein expression in mouse mammary cells
(The University of Waikato, 1998)The regulation of milk protein gene expression in mammary epithelial cells occurs in response to multiple hormonal signals, plus cell-matrix and cell-cell interactions. A number of signalling molecules have been implicated ... -
Retroviruses in the common brush-tailed possum (Trichosurus vulpecula)
(The University of Waikato, 1999)This study details the search for, and characterisation of, retroviruses in a marsupial, the common brush-tailed possum (Trichosurus vulpecula). Initial efforts were directed at detecting exogenous retroviruses in possums, ... -
The role of growth factors in the regeneration of skeletal muscle
(The University of Waikato, 2001)The overall aim of this thesis was to examine myostatin and components of the insulin-like growth factor (IGF) axis during regeneration, to determine whether these factors were temporally regulated during regeneration, ...
