| dc.contributor.author | Kavtaradze, Levan K. | en_US |
| dc.contributor.author | Manley-Harris, Merilyn | en_US |
| dc.contributor.author | Nicholson, Brian K. | en_US |
| dc.coverage.spatial | United States | en_NZ |
| dc.date.accessioned | 2008-03-19T05:11:01Z | |
| dc.date.available | 2007-12-11 | en_US |
| dc.date.available | 2008-03-19T05:11:01Z | |
| dc.date.issued | 2004-01-01 | en_US |
| dc.identifier.citation | Kavtaradze, L.K., Manley-Harris, M. & Nicholson, B.K. (2004). Efficient routes to epimerically-pure side-chain derivatives of lanosterol. Steroids, 69, 227-233. | en_US |
| dc.identifier.uri | https://hdl.handle.net/10289/189 | |
| dc.description.abstract | A technically simple route is described to individual epimers of side-chain derivatives of lanosterol (3-hydroxy-5-lanosta-8,24-diene). Epimerically pure 24,25-epoxy-, 24,25-dihydroxy- and 24-bromo-25-hydroxy-lanosterol have been prepared in good yield from commercial (50-60%) lanosterol. Hypophosphorous acid was used as a catalyst for the cohalogenation of the 24(25) bond and also for the efficient conversion of 24,25-epoxy- and 24-bromo-25-hydroxylanosterol to epimerically pure 24(R) or 24(S)-24,25-dihydroxylanosterols. | en_US |
| dc.format.mimetype | application/pdf | |
| dc.language.iso | en | |
| dc.publisher | Elsevier | en_NZ |
| dc.relation.uri | http://www.elsevier.com/wps/find/journaldescription.cws_home/504090/description#description | en_US |
| dc.rights | This is an authors version of an article published in the journal, Steroids, (c) 2004 Elsevier Inc. | en_US |
| dc.title | Efficient routes to epimerically-pure side-chain derivatives of lanosterol | en_US |
| dc.type | Journal Article | en_US |
| dc.identifier.doi | 10.1016/j.steroids.2003.12.004 | en_US |
| dc.relation.isPartOf | Steroids | en_NZ |
| pubs.begin-page | 227 | en_NZ |
| pubs.elements-id | 30030 | |
| pubs.end-page | 233 | en_NZ |
| pubs.issue | 4 | en_NZ |
| pubs.volume | 69 | en_NZ |
