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dc.contributor.authorLloyd, Nicholas C.en_US
dc.contributor.authorMorgan, Hugh W.en_US
dc.contributor.authorNicholson, Brian K.en_US
dc.contributor.authorRonimus, Ron S.en_US
dc.coverage.spatialGermanyen_NZ
dc.date.accessioned2008-03-19T05:08:13Z
dc.date.available2007-08-30en_US
dc.date.available2008-03-19T05:08:13Z
dc.date.issued2004-08-01en_US
dc.identifier.citationLloyd, N.C., Morgan, H.W., Nicholson, B.K. & Ronimus, R.S. (2005). The composition of Ehrlichs Salvarsan; resolution of a century-old debate, Angew. Chem. Int. Ed., 44, 941-944.en_US
dc.identifier.urihttps://hdl.handle.net/10289/207
dc.description.abstractEhrlich introduced in 1910 the compound 3-amino-4-hydroxyphenylarsenic(I) [Salvarsan, arsphenamine, Ehrlich 606,] as a remedy for syphilis, a disease caused by the spirochaete bacterium Treponema pallidum. His methodical search for a specific curative for an identified disease can be regarded as the introduction of targeted chemotherapy.en_US
dc.format.mimetypeapplication/pdf
dc.language.isoen
dc.publisherWiley-VCH Verlag GmbH & Co. KGaAen_NZ
dc.relation.urihttp://www3.interscience.wiley.com/cgi-bin/jhome/26737en_US
dc.rightsThis document is the authors version. The final definitive version is published in the journal, Angewandte Chemie International Edition, (c) 2005 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.en_US
dc.subjectarsenicen_US
dc.subjectarsphenamineen_US
dc.subjectmass spectrometryen_US
dc.subjectsalvarsanen_US
dc.subjectstructure elucidationen_US
dc.titleThe composition of Ehrlich's salvarsan: Resolution of a century-old debateen_US
dc.typeJournal Articleen_US
dc.identifier.doi10.1002/anie.200461471en_US
dc.relation.isPartOfAngewandte Chemie International Editionen_NZ
pubs.begin-page941en_NZ
pubs.elements-id30404
pubs.end-page944en_NZ
pubs.issue6en_NZ
pubs.volume44en_NZ


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