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dc.contributor.authorGoss, Carol H. A.
dc.contributor.authorHenderson, William
dc.contributor.authorWilkins, Alistair L.
dc.contributor.authorEvans, Cameron
dc.date.accessioned2009-11-24T19:43:13Z
dc.date.available2009-11-24T19:43:13Z
dc.date.issued2003
dc.identifier.citationGoss, C. H. A., Henderson, W., Wilkins, A. L., & Evans, C. (2003). Synthesis, characterisation and biological activity of gold(III) catecholate and related complexes. Journal of Organometallic Chemistry, 679(2), 194-201.en
dc.identifier.urihttps://hdl.handle.net/10289/3408
dc.description.abstractThe reactions of the cyclometallated gold(III) complexes [LAuCl₂] [L=2-(dimethylaminomethyl)phenyl, 2-benzylpyridyl or 2-anilinopyridyl] with catechol, tetrachlorocatechol, or the cyclic α,β-diketone SCH(CO2Et)C(O)C(O)CH(CO2Et) give stable complexes containing five-membered Au-O-C-C-O rings. These represent the first examples of well-characterised gold(III) catecholate complexes. Similarly, reactions with 2-acetamidophenol [HOC₆H₄NHC(O)CH₃] give complexes with the related Au---N---C---C---O ring. The complexes were characterised by NMR spectroscopy, electrospray ionisation mass spectrometry, elemental microanalysis, and in the case of the complex [(2-benzylpyridyl)Au{OC₆H₄NC(O)CH₃}] by an X-ray crystal structure determination. Several complexes show high activity towards P388 murine leukemia cells.en
dc.format.mimetypeapplication/pdf
dc.language.isoen
dc.publisherElsevier S.A.en_NZ
dc.rightsThis is an author’s accepted version of an article published in the Journal of Organometallic Chemistry. Copyright © 2003 Elsevier B.V. All rights reserved.en
dc.subjectgolden
dc.subjectcyclometallated complexesen
dc.subjectcatecholate complexesen
dc.subjectbiological activityen
dc.titleSynthesis, characterisation and biological activity of gold(III) catecholate and related complexesen
dc.typeJournal Articleen
dc.identifier.doi10.1016/S0022-328X(03)00585-0en
dc.relation.isPartOfJournal of Organometallic Chemistryen_NZ
pubs.begin-page194en_NZ
pubs.elements-id29439
pubs.end-page201en_NZ
pubs.issue2en_NZ
pubs.volume679en_NZ


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