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dc.contributor.authorTonks, A.
dc.contributor.authorCooper, Rose A.
dc.contributor.authorPrice, A.J.
dc.contributor.authorMolan, Peter C.
dc.contributor.authorJones, K.P.
dc.coverage.spatialUnited Statesen_NZ
dc.date.accessioned2011-05-25T22:32:16Z
dc.date.available2011-05-25T22:32:16Z
dc.date.issued2001
dc.identifier.citationTonks, A., Cooper, R.A., Price, A.J., Molan, P.C. & Jones, K.P. (2001). Stimulation of TNF-α release in monocytes by honey. Cytokine, 14(4), 240-242.en_NZ
dc.identifier.urihttps://hdl.handle.net/10289/5359
dc.description.abstractAlthough evidence exists for the antibacterial effects of honey there is limited objective evidence for direct promotion of healing. We investigated the effect of manuka, pasture and an artificial honey on macrophage function. Reactive oxygen intermediate (ROI) production was assessed by luminol enhanced chemoluminescence and tumour necrosis factor-alpha (TNF-α) release was determined by immunoassay. ROI production was significantly (P<0.001) decreased by pasture honey and manuka honey. TNF-α release was significantly enhanced (P<0.001) in unprimed MM6 cells by manuka and pasture honey but was not altered in primed cells. These results could explain the suggested therapeutic properties of honey in promoting wound healing.en_NZ
dc.language.isoen
dc.publisherElsevier
dc.relation.urihttp://www.sciencedirect.com/science/article/pii/S1043466601908683en_NZ
dc.subjecthoneyen_NZ
dc.subjectmacrophageen_NZ
dc.subjectmonocyteen_NZ
dc.subjectrespiratory bursten_NZ
dc.subjecttumour necrosis factor alpha (TNF-α)en_NZ
dc.titleStimulation of TNF-α release in monocytes by honeyen_NZ
dc.typeJournal Articleen_NZ
dc.identifier.doi10.1006/cyto.2001.0868en_NZ
dc.relation.isPartOfCytokineen_NZ
pubs.begin-page240en_NZ
pubs.elements-id42213
pubs.end-page242en_NZ
pubs.issue4en_NZ
pubs.volume14en_NZ


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