Research Commons
      • Browse 
        • Communities & Collections
        • Titles
        • Authors
        • By Issue Date
        • Subjects
        • Types
        • Series
      • Help 
        • About
        • Collection Policy
        • OA Mandate Guidelines
        • Guidelines FAQ
        • Contact Us
      • My Account 
        • Sign In
        • Register
      View Item 
      •   Research Commons
      • University of Waikato Research
      • Science and Engineering
      • Science and Engineering Papers
      • View Item
      •   Research Commons
      • University of Waikato Research
      • Science and Engineering
      • Science and Engineering Papers
      • View Item
      JavaScript is disabled for your browser. Some features of this site may not work without it.

      Melt-extruded polyethylene oxide (PEO) rods as drug delivery vehicles: Formulation, performance as controlled release devices and the influence of co-extruded excipients on drug release profiles

      Mucalo, Michael R.; Rathbone, Michael J.
      Thumbnail
      Files
      Mucalo 2012 Melt-extruded.pdf
      1.457Mb
      Link
       www.nzic.org.nz
      Find in your library  
      Citation
      Export citation
      Mucalo, M.R. & Rathbone, M.J. (2012). Melt-extruded polyethylene oxide (PEO) rods as drug delivery vehicles: Formulation, performance as controlled release devices and the influence of co-extruded excipients on drug release profiles. Chemistry in New Zealand, 76(3), 85-95.
      Permanent Research Commons link: https://hdl.handle.net/10289/7524
      Abstract
      The utility of controlled release medication formulations lies in their ability to keep drugs at steady levels in the blood plasma of recipients and within the termini of the maximum and minimum effective therapeutic levels. This avoids the “ups” and “downs” of medication levels within the body which would have been the result had conventional immediate release tablets been administered instead. In the veterinary field, controlled release medications are essential¹ because of the logistical difficulties of administering drugs on a regular (e.g., daily) basis to animals. The chief advantages of controlled release veterinary medications lie in the ease with which they can be administered; decrease in stress for animals, owing to less need for rounding up and frequent dosing; and, most importantly for farmers, the reduced cost of treatment relative to that for a multiple dosage regime.
      Date
      2012
      Type
      Journal Article
      Publisher
      New Zealand Institute of Chemistry
      Rights
      This article is published in Chemistry in New Zealand. © 2012 New Zealand Institute of Chemistry.
      Collections
      • Science and Engineering Papers [3019]
      Show full item record  

      Usage

      Downloads, last 12 months
      20
       
       

      Usage Statistics

      For this itemFor all of Research Commons

      The University of Waikato - Te Whare Wānanga o WaikatoFeedback and RequestsCopyright and Legal Statement