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dc.contributor.authorChau, Rocky
dc.contributor.authorKalaitzis, John
dc.contributor.authorWood, Susanna A.
dc.contributor.authorNeilan, Brett
dc.date.accessioned2013-12-17T01:38:25Z
dc.date.available2013-12-17T01:38:25Z
dc.date.copyright2013-08-02
dc.date.issued2013
dc.identifier.citationChau, R., Kalaitzis, J. A., Wood, S. A., & Neilan, B. A. (2013). Diversity and biosynthetic potential of culturable microbes associated with toxic marine animals. Marine drugs, 11(8), 2695-2712.en_NZ
dc.identifier.urihttps://hdl.handle.net/10289/8356
dc.description.abstractTetrodotoxin (TTX) is a neurotoxin that has been reported from taxonomically diverse organisms across 14 different phyla. The biogenic origin of tetrodotoxin is still disputed, however, TTX biosynthesis by host-associated bacteria has been reported. An investigation into the culturable microbial populations from the TTX-associated blue-ringed octopus Hapalochlaena sp. and sea slug Pleurobranchaea maculata revealed a surprisingly high microbial diversity. Although TTX was not detected among the cultured isolates, PCR screening identifiedsome natural product biosynthesis genes putatively involved in its assembly. This study is the first to report on the microbial diversity of culturable communities from H. maculosa and P. maculata and common natural product biosynthesis genes from their microbiota. We also reassess the production of TTX reported from three bacterial strains isolated from the TTX-containing gastropod Nassarius semiplicatus.en_NZ
dc.format.mimetypeapplication/pdf
dc.language.isoenen_NZ
dc.relation.ispartofMarine Drugs
dc.relation.urihttp://www.mdpi.com/1660-3397/11/8/2695en_NZ
dc.subjecttetrodotoxinen_NZ
dc.subjectbiosynthesisen_NZ
dc.subjectmicrobial diversityen_NZ
dc.subjectPleurobranchaea maculateen_NZ
dc.subjectHapalochlaena sp.en_NZ
dc.subjectNassarius semiplicatusen_NZ
dc.titleDiversity and biosynthetic potential of culturable microbes associated with toxic marine animalsen_NZ
dc.typeJournal Articleen_NZ
dc.identifier.doi10.3390/md11082695en_NZ


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