Tan, Kean SianCervin, MattiLeman, PatrickNielsen, KristopherKumar, Prashanth VasanthaMedvedev, Oleg N.2025-09-152025-09-152025Tan, K. S., Cervin, M., Leman, P., Nielsen, K., Kumar, P. V., & Medvedev, O. (2025). AI meets psychology: an exploratory study of large language models’ competence in psychotherapy contexts. Journal of Psychology and AI, 1(1), Article 2545258. https://doi.org/10.1080/29974100.2025.2545258https://hdl.handle.net/10289/17655The increasing prevalence of mental health problems coupled with limited access to professional support has prompted exploration of technological solutions. Large Language Models (LLMs) represent a potential tool to address these challenges, yet their capabilities in psychotherapeutic contexts remain unclear. This study examined the competencies of current LLMs in psychotherapy-related tasks including alignment with evidence-informed clinical standards in case formulation, treatment planning, and implementation. Using an exploratory mixed-methods design, we presented three clinical cases (depression, anxiety, stress) and 12 therapy-related prompts to seven LLMs: ChatGPT-4o, ChatGPT-4, Claude 3.5 Sonnet, Claude 3 Opus, Meta Llama 3.1, Google Gemini 1.5 Pro, and Microsoft Co-pilot. Responses were evaluated by five experienced clinical psychologists using quantitative ratings and qualitative feedback. No single model consistently produced high-quality responses across all tasks, though different models showed distinct strengths. Models performed better in structured tasks such as determining session length and discussing goal-setting but struggled with integrative clinical reasoning and treatment implementation. Higher-rated responses demonstrated clinical humility, maintained therapeutic boundaries, and recognised therapy as collaborative. Current LLMs are more promising as supportive tools for clinicians than as therapeutic applications. This paper highlights key areas for development needed to enhance clinical reasoning abilities for effective mental health use.enAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/Journal Article10.1080/29974100.2025.25452582997-41005203 Clinical and Health Psychology52 Psychology3 Good Health and Well Being