Depree, Gary J.Main, LyndsayNicholson, Brian K.Robinson, Nicholas P.Jameson, Geoffrey B.2008-03-192007-08-302008-03-192006-02-01Depree, G.J., Main, L., Nicholson, B.K., Robinson, N.P. & Jameson, G.B. (2006). Synthesis and alkyne-coupling chemistry of cyclomanganated 1- and 3-acetylindoles, 3-formylindole and analogues, Journal of Organometallic Chemistry, 691, 667-679.https://hdl.handle.net/10289/149The syntheses are reported of new cyclomanganated indole derivatives (1-acetyl-κO-indolyl-κC2)dicarbonylbis(trimethylphosphite)manganese (2), (1-methyl-3-acetyl-κO-indolyl-κC2)tetracarbonylmanganese (4), (3-formyl-κO-indolyl-κC2)tetracarbonylmanganese (5a) and (1-methyl-3-formyl-κO-indolyl-κC2)tetracarbonylmanganese (5b). The unusually complicated crystal structure of 5b has been determined, the first for a cyclomanganated aryl aldehyde. The preparations of a mitomycin-related pyrrolo-indole and related products by thermally promoted and oxidatively (Me3NO) initiated alkyne-coupling reactions of the previously known complex (1-acetyl-κO-indolyl-κC2)tetracarbonylmanganese (1) are reported for different alkynes and solvents. X-ray crystal structures are reported for the dimethyl acetylenedicarboxylate coupling product of 1 (dimethyl 1-methyl-l-hydroxypyrrolo[1,2a]-indole-2,3-dicarboxylate; 6a), and an unusually-cyclised triple insertion product 8 from the coupling of acetylene with 4, in which a cyclopentadiene moiety is η3-allyl-coordinated to Mn through only one double bond and an exocyclic carbon, but which rearranges on heating to an η5-cyclopentadienyl complex.application/pdfenThis is an authors version of an article published in the, Journal of Organometallic Chemistry, (c) 2005 Elsevier Science B.V.cyclometallationmanganeseindolesalkyne couplingJournal Article10.1016/j.jorganchem.2005.09.049