Lloyd, Nicholas C.Morgan, Hugh W.Nicholson, Brian K.Ronimus, Ron S.2008-03-192007-08-302008-03-192004-08-01Lloyd, N.C., Morgan, H.W., Nicholson, B.K. & Ronimus, R.S. (2005). The composition of Ehrlichs Salvarsan; resolution of a century-old debate, Angew. Chem. Int. Ed., 44, 941-944.https://hdl.handle.net/10289/207Ehrlich introduced in 1910 the compound 3-amino-4-hydroxyphenylarsenic(I) [Salvarsan, arsphenamine, Ehrlich 606,] as a remedy for syphilis, a disease caused by the spirochaete bacterium Treponema pallidum. His methodical search for a specific curative for an identified disease can be regarded as the introduction of targeted chemotherapy.application/pdfenThis document is the authors version. The final definitive version is published in the journal, Angewandte Chemie International Edition, (c) 2005 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.arsenicarsphenaminemass spectrometrysalvarsanstructure elucidationJournal Article10.1002/anie.200461471