Calcium modeling and TMS variability

Abstract

• We have modelled Calcium-dependent plasticity with a Neural Field scheme • Developed the approach further to modelling MEPs • Modelling can reproduce MEP ranges from submillivolt to ~10 mV • Modelling can reproduce both potentiation and depression following cTBS and iTBS • In terms of variability of MEPs, the following are important: • TMS-to-e coupling strength (parameter μ) • Excitatory-to-excitatory coupling strength wee • Number of pulses / time since stimulation • Include reporting of actual thresholds when %RMT is used