This regional report is a part of a larger project, The Canadian Trans Youth Health Survey. Researchers from universities and other organizations in Canada created the survey, which was administered online to 923 participants across Canada, with 67 respondents coming from the Prairie Provinces (Saskatchewan & Manitoba). Two different surveys were distributed: one to younger (14-18 years) and the other to older (19-25 years) youth. The focus of the survey was the physical and mental health of trans youth, as well as factors that affect health of trans youth. The regional report represents the results from the Prairie Provinces of Canada.