Show simple item record  

dc.contributor.authorMcDougall, S.
dc.contributor.authorAgnew, K. E.
dc.contributor.authorCursons, Raymond T.
dc.contributor.authorHou, X. X.
dc.contributor.authorCompton, C. R. W.
dc.coverage.spatialUnited Statesen_NZ
dc.date.accessioned2009-07-15T22:20:13Z
dc.date.available2009-07-15T22:20:13Z
dc.date.issued2008
dc.identifier.citationMcDougall, S., Agnew, K.E., Cursons, R., Hou, X. X. & Compton, C. R. W. (2008).en
dc.identifier.urihttps://hdl.handle.net/10289/2679
dc.description.abstractThe objective of this study was to compare the clinical and bacteriological cure rates of cows with clinical mastitis following treatment with either tylosin base (5 g injected 3 times at 24-h intervals; n = 306) or penethamate hydriodide (5 g injected 3 times at 24-h intervals; n = 289). Duplicate milk samples were collected before treatment and again 14 ± 3 and 21 ± 3 d later for microbiological analysis. Only those quarters from which gram-positive mastitis pathogens were isolated before treatment were included in the analyses. Streptococcus uberis was the most prevalent isolate. The number of cows with clinical failure (i.e., retreated within 21 d of enrollment) did not differ between treatments (64 vs. 63, respectively). At the quarter level, there was no difference in the proportion of bacteriological cure between treatments (81.2 vs. 83.8% for penethamate hydriodide or tylosin, respectively). The proportions of clinical and bacteriological cure were influenced by age, herd, severity of mastitis, number of glands within the cow with clinical mastitis, bacterial species, and days postpartum at enrollment. There was no difference between treatment groups for SCC (4.46 vs. 4.44 ± 0.08, mean ± standard error of the difference in ln SCC for cows treated with penethamate hydriodide or tylosin, respectively) or production of milk solids (1.45 vs. 1.48 ± 0.02 kg/d of milk fat + protein, for the penethamate hydriodide or tylosin treatment, respectively). Overall, there was no difference in the proportions of clinical failure (17.3 vs. 16.5% of cows treated with penethamate hydriodide or tylosin, respectively) or bacteriological cure (79.8 vs. 82.0% of cows treated with penethamate hydriodide or tylosin, respectively), or in SCC or milk production between dairy cows with clinical mastitis and those treated for clinical mastitis with 1 of 2 parenteral antibiotic therapies.en
dc.language.isoen
dc.publisherAmerican Dairy Science Associationen_NZ
dc.relation.urihttp://jds.fass.org/cgi/content/full/90/2/779en
dc.subjectmastitisen
dc.subjectantibioticen
dc.subjectbacteriologyen
dc.subjecttherapyen
dc.titleParenteral treatment of clinical mastitis with tylosin base or penethamate hydriodide in dairy cattleen
dc.typeJournal Articleen
dc.identifier.doi10.3168/jds.S0022-0302(07)71562-Xen_NZ
dc.relation.isPartOfJournal of Dairy Scienceen_NZ
pubs.begin-page779en_NZ
pubs.elements-id34049
pubs.end-page789en_NZ
pubs.issue2en_NZ
pubs.volume90en_NZ


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record