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dc.contributor.authorHan, Sangmi
dc.contributor.authorYeo, Joohong
dc.contributor.authorBaek, Haju
dc.contributor.authorLin, Shih-Min (Sam)
dc.contributor.authorMeyer, Stacy
dc.contributor.authorMolan, Peter C.
dc.date.accessioned2010-07-07T02:34:21Z
dc.date.available2010-07-07T02:34:21Z
dc.date.issued2009
dc.identifier.citationHan, S., Yeo, J., Baek, H., Lin, S.-M., Meyer, S. & Molan, P. (2009). Postantibiotic effect of purified melittin from honeybee (Apis mellifera) venom against Escherichia coli and Staphylococcus aureus. Journal of Asian Natural Products Research, 11(9), 796-804.en_NZ
dc.identifier.urihttps://hdl.handle.net/10289/4107
dc.description.abstractSince the ancient times, the antibacterial application of honeybee venom (BV) has been practised and persisted. We investigated the antibacterial activity of whole BV and purified melittin against Escherichia coli and Staphylococcus aureus by the minimum inhibitory concentrations (MICs) and the postantibiotic effects (PAEs). The in vitro PAEs of whole BV and isolated melittin were determined using E. coli and S. aureus. The PAEs of whole BV against E. coli and S. aureus were 0.15 h (1 MIC), 2.4 h (5 MIC), and 3.45 h (1 MIC), respectively. The PAEs of melittin against E. coli and S. aureus were 0.1 h (1 MIC), 3.2 h (5 MIC), and 4.35 h (1 MIC), respectively. These results suggest that whole BV and melittin will be developed as a novel antibacterial drug.en_NZ
dc.language.isoen
dc.publisherTaylor & Francis Groupen_NZ
dc.relation.urihttp://www.informaworld.com/smpp/content~content=a914967585~db=all~jumptype=rssen_NZ
dc.subjectbee venomen_NZ
dc.subjectmelittinen_NZ
dc.subjectminimum inhibitory concentrationen_NZ
dc.subjectpostantibiotic effecten_NZ
dc.titlePostantibiotic effect of purified melittin from honeybee (Apis mellifera) venom against Escherichia coli and Staphylococcus aureusen_NZ
dc.typeJournal Articleen_NZ
dc.identifier.doi10.1080/10286020903164277en_NZ
dc.relation.isPartOfJournal of Asian Natural Products Researchen_NZ
pubs.begin-page796en_NZ
pubs.elements-id35019
pubs.end-page804en_NZ
pubs.issue9en_NZ
pubs.volume11en_NZ


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