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dc.contributor.authorDaniel, Roy M.
dc.contributor.authorDanson, Michael J.
dc.contributor.authorEisenthal, Robert
dc.contributor.authorLee, Charles Kai-Wu
dc.contributor.authorPeterson, Michelle E.
dc.date.accessioned2010-08-26T21:51:56Z
dc.date.available2010-08-26T21:51:56Z
dc.date.issued2007
dc.identifier.citationDaniel, R.M., Danson, M.J., Eisenthal, R., Lee, C.K. & Peterson, M.E. (2007). Review: The effect of temperature on enzyme activity: new insights and their implications. Extremophiles, 12(1), 51-59.en_NZ
dc.identifier.urihttps://hdl.handle.net/10289/4439
dc.description.abstractThe two established thermal properties of enzymes are their activation energy and their thermal stability. Arising from careful measurements of the thermal behaviour of enzymes, a new model, the Equilibrium Model, has been developed to explain more fully the effects of temperature on enzymes. The model describes the effect of temperature on enzyme activity in terms of a rapidly reversible active-inactive transition, in addition to an irreversible thermal inactivation. Two new thermal parameters, T eq and ΔH eq, describe the active–inactive transition, and enable a complete description of the effect of temperature on enzyme activity. We review here the Model itself, methods for the determination of T eq and ΔH eq, and the implications of the Model for the environmental adaptation and evolution of enzymes, and for biotechnology.en_NZ
dc.language.isoen
dc.relation.urihttp://www.springerlink.com/content/d2x417361w723634/en_NZ
dc.subjectEquilibrium Modelen_NZ
dc.subjecttemperatureen_NZ
dc.subjectenzymeen_NZ
dc.subjectadaptationen_NZ
dc.subjectevolutionen_NZ
dc.subjecttemperature optimumen_NZ
dc.subjectstabilityen_NZ
dc.subjectdenaturationen_NZ
dc.subjectT eqen_NZ
dc.subjectΔH eqen_NZ
dc.titleReview: The effect of temperature on enzyme activity: new insights and their implicationsen_NZ
dc.typeJournal Articleen_NZ
dc.identifier.doi10.1007/s00792-007-0089-7en_NZ
pubs.declined2014-06-05T17:47:34.814+1200
pubs.deleted2014-06-05T17:47:34.814+1200
pubs.elements-id35284


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