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      A general method for the synthesis of peptidyl substrate for proteolytic enzymes

      Whitmore, Andrew; Daniel, Roy M.; Petach, Helen H.
      DOI
       10.1016/0040-4039(94)02290-R
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      Whitmore, A., Daniel, R.M. & Petach, H.H. (1995). A general method for the synthesis of peptidyl substrate for proteolytic enzymes. Tetrahedron Letters, 36(3), 475-476.
      Permanent Research Commons link: https://hdl.handle.net/10289/4469
      Abstract
      The synthesis of an heterogeneous peptide substrate for the assay of proteases was carried out by cleaving a protein using a protease to generate small peptides which were then coupled to a chromophore, p-nitroaniline. The chromophoric peptide product could be used to assay for the protease which produced the original peptides.
      Date
      1995
      Type
      Journal Article
      Publisher
      Elsevier
      Collections
      • Science and Engineering Papers [3077]
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