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      MALDI-TOF mass spectrometry of Cyanobacteria: a global approach to the discovery of novel secondary metabolites

      Puddick, Jonathan; Prinsep, Michèle R.
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      MALDI_TOF.pdf
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       nzic.org.nz
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      Puddick, J. & Prinsep, M.R. (2008). MALDI-TOF mass spectrometry of Cyanobacteria: a global approach to the discovery of novel secondary metabolites. Chemistry in New Zealand, 72(2), 68-71.
      Permanent Research Commons link: https://hdl.handle.net/10289/4576
      Abstract
      Cyanobacteria (blue-green algae) are a group of ancient prokaryotic organisms dating back between three and four billion years.¹ They have been attributed with oxygenating the earth’s atmosphere² but, since the anthropogenic euthrophication of lakes, ponds and oceans, they have become synonymous with water hygiene issues.³ This is due to the alteration of the nutrient composition of their habitat to one which is optimal for growth (or blooms). Cyanobacterial blooms may simply cause foul tastes and odours,⁴ but they can also lead to the production of toxic secondary metabolites poisonous to humans and animals upon ingestion.⁵ NZ has yet to suffer a human fatality, but the deaths of several dogs in Wellington was attributed to homoanatoxin-a 1 (Chart 1) from a Phormidium species.⁶
      Date
      2008
      Type
      Journal Article
      Publisher
      New Zealand Institute of Chemistry
      Rights
      This article has been published in the journal: Chemistry in New Zealand. Used with permission.
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      • Science and Engineering Papers [2945]
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