Molecular adaptations to psychrophily: the impact of ‘omic’ technologies

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dc.contributor.authorCasanueva, Ana
dc.contributor.authorTuffin, Marla I.
dc.contributor.authorCary, S. Craig
dc.contributor.authorCowan, Don A.
dc.date.accessioned2010-07-05T03:19:36Z
dc.date.available2010-07-05T03:19:36Z
dc.date.issued2010
dc.description.abstractThe ability of cold-adapted microorganisms (generally referred to as psychrophiles) to survive is the result of molecular evolution and adaptations which, together, counteract the potentially deleterious effects of low kinetic energy environments and the freezing of water. These physiological adaptations are seen at many levels. Against a background of detailed comparative protein structural analyses, the recent surge of psychrophile proteome, genome, metagenome and transcriptome sequence data has triggered a series of sophisticated analyses of changes in global protein composition. These studies have revealed consistent and statistically robust changes in amino acid composition, interpreted as evolutionary mechanisms designed to destabilise protein structures, as well as identifying the presence of novel genes involved in cold adaptation.en_NZ
dc.identifier.citationCasanueva, A., Tuffin, M., Cary, C. & Cowan, D.A. (2010). Molecular adaptations to psychrophily: the impact of ‘omic’ technologies. Trends in Microbiology, published online on 18 June 2010.en_NZ
dc.identifier.doi10.1016/j.tim.2010.05.002en_NZ
dc.identifier.urihttps://hdl.handle.net/10289/4094
dc.language.isoen
dc.publisherElsevieren_NZ
dc.relation.isPartOfTrends in Microbiologyen_NZ
dc.subjectmolecular adaptationsen_NZ
dc.subjectadaptationsen_NZ
dc.subjectpsychrophilesen_NZ
dc.titleMolecular adaptations to psychrophily: the impact of ‘omic’ technologiesen_NZ
dc.typeJournal Articleen_NZ
pubs.begin-page1en_NZ
pubs.elements-id35031
pubs.end-page8en_NZ
pubs.issue8en_NZ
pubs.volumeonlineen_NZ
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