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dc.contributor.authorTill, Marisaen_NZ
dc.date.accessioned2007-03-06T13:50:51Z
dc.date.available2007-08-21T16:56:03Z
dc.date.issued2007en_NZ
dc.identifier.citationTill, M. (2007). Studies of New Zealand Marine Organisms (Thesis, Master of Science (MSc)). The University of Waikato, Hamilton, New Zealand. Retrieved from https://hdl.handle.net/10289/2498en
dc.identifier.urihttps://hdl.handle.net/10289/2498
dc.description.abstractThe chemical study of three New Zealand marine organisms is described, along with a survey of the chemistry and biological activity of eighty-five marine organisms collected from New Zealand waters. The study of the New Zealand marine bryozoan Pterocella vesiculosa has resulted in the isolation of three new compounds; pterocellin H, pterocellin I and 1-methyl-5-bromo-8-methoxy-β-carboline. These compounds were characterised using high resolution mass spectrometry, one- and two-dimensional nuclear magnetic resonance spectroscopy and X-ray crystallography. The biological activity of these compounds was investigated and a discussion of the results including a comparison with the activity of closely related compounds is also presented. The crude extracts of eighty-five marine organisms were surveyed to establish their biological activity and chemical constituents. The results of this study indicated which species had interesting biological activity. The chemical survey allowed geographical and intra-species comparisons of chemical constituents between samples, as well as potentially indicating the presence of known secondary metabolites. For the Pterocella vesiculosa samples the survey methodology clearly illustrated the presence of pterocellins A and B. Two marine organisms were chosen for further investigation based on their biological activity and chemical survey results. Bioactivity directed isolation procedures yielded no new compounds from the organisms. The sterol composition of these species is also presented.en_NZ
dc.format.mimetypeapplication/pdf
dc.language.isoen
dc.publisherThe University of Waikatoen_NZ
dc.rightsAll items in Research Commons are provided for private study and research purposes and are protected by copyright with all rights reserved unless otherwise indicated.
dc.subjectNatural productsen_NZ
dc.subjectmarine organismsen_NZ
dc.subjectbryozoanen_NZ
dc.subjectpterocellinen_NZ
dc.subjectpterocella vesiculosaen_NZ
dc.subjectalkaloidsen_NZ
dc.subjectbeta-carbolineen_NZ
dc.subjectsecondary metabolitesen_NZ
dc.titleStudies of New Zealand Marine Organismsen_NZ
dc.typeThesisen_NZ
thesis.degree.disciplineScience and Engineeringen_NZ
thesis.degree.grantorUniversity of Waikatoen_NZ
thesis.degree.levelMasters
thesis.degree.nameMaster of Science (MSc)en_NZ
uow.date.accession2007-03-06T13:50:51Zen_NZ
uow.date.available2007-08-21T16:56:03Zen_NZ
uow.identifier.adthttp://adt.waikato.ac.nz/public/adt-uow20070306.135051en_NZ
uow.date.migrated2009-06-09T23:30:42Zen_NZ
pubs.place-of-publicationHamilton, New Zealanden_NZ


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