dc.contributor.author | Barker-Collo, Suzanne | |
dc.contributor.author | Starkey, Nicola J. | |
dc.contributor.author | Theadom, Alice | |
dc.coverage.spatial | England | en_NZ |
dc.date.accessioned | 2014-12-12T02:01:15Z | |
dc.date.available | 2013 | |
dc.date.available | 2014-12-12T02:01:15Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Barker-Collo, S., Starkey, N. J., & Theadom, A. (2013). Treatment for depression following mild traumatic brain injury in adults: A meta-analysis. Brain Injury, 27(10), 1124–1133. http://doi.org/10.3109/02699052.2013.801513 | en |
dc.identifier.uri | https://hdl.handle.net/10289/8957 | |
dc.description.abstract | Primary objective: Development of depression after TBI is linked to poorer outcomes. The aim of this manuscript is to review evidence for the effectiveness of current treatments.
Research design: Two meta-analyses were undertaken to examine the effectiveness of both pharmacological and non-pharmacological interventions for depression after mild TBI
Method and procedures: PubMed, Medline, PsychInfo, Web of Science and Digital Dissertations were searched and 13 studies located. Meta Analyst Beta 3.13 was used to conduct analyses of pre- vs post-effects then to examine treatment group vs control group effects.
Main outcomes and results: Studies using a pre–post design produced an overall effect size of 1.89 (95% CI = 1.20–2.58, p < 0.001), suggesting that treatments were effective; however, the overall effect for controlled trials was 0.46 (95% CI = −0.44–1.36, p < 0.001), which favoured the control rather than treatment groups.
Conclusions: This study highlights the need for additional large well-controlled trials of effective treatments for depression post-TBI. | |
dc.format.extent | 1124 - 1133 (10) | |
dc.format.mimetype | application/pdf | |
dc.publisher | INFORMA HEALTHCARE | en_NZ |
dc.rights | This is an author’s accepted version of an article published in the journal: Brain Injury. © 2013 Informa UK Ltd. | |
dc.subject | CBT | |
dc.subject | Meta-analysis | |
dc.subject | TBI | |
dc.subject | antidepressants | |
dc.subject | depression | |
dc.subject | interventions | |
dc.subject | mild brain injury | |
dc.subject | treatment | |
dc.title | Treatment for depression following mild traumatic brain injury in adults: A meta-analysis | |
dc.type | Journal Article | |
dc.identifier.doi | 10.3109/02699052.2013.801513 | |
dc.relation.isPartOf | Brain Injury | |
pubs.begin-page | 1124 | |
pubs.elements-id | 38691 | |
pubs.end-page | 1133 | |
pubs.issue | 10 | |
pubs.volume | 27 | |