Executive dysfunction and cognitive impairment in a large community-based sample with Multiple Sclerosis from New Zealand: A descriptive study

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dc.contributor.authorDrew, Margaret A.
dc.contributor.authorTippett, Lynette J.
dc.contributor.authorStarkey, Nicola J.
dc.contributor.authorIsler, Robert B.
dc.coverage.spatialUnited Statesen_NZ
dc.date.accessioned2013-11-21T01:03:11Z
dc.date.available2013-11-21T01:03:11Z
dc.date.copyright2008-01
dc.date.issued2008
dc.description.abstractMultiple Sclerosis (MS) is one of the most common chronic diseases of the central nervous system, and in New Zealand an estimated 4000 people are currently affected. This study was conducted to examine executive functioning, memory and general ability in a community-based sample of 95 participants with MS. The sample included those with relapsing–remitting, secondary progressive, chronic progressive and benign MS with an average duration of illness of 11.8 years. Only 9% of the participants showed no indication of cognitive impairment with most exhibiting mild executive dysfunction across the range of shifting, inhibition, fluency and working memory categories. As this became more widespread, all other measures of cognitive ability and memory also showed evidence of deterioration, but in some, this may have been due to slowed information processing. Overall, there was a high degree of variability in the levels of performance and there was no ‘typical’ pattern of deficits associated with MS. Thus, a proportion of those living with MS may have to cope with noticeable and unpredictable cognitive decline in addition to their physical disabilities.en_NZ
dc.identifier.citationDrew, M., Tippett, L. J., Starkey, N. J., & Isler, R. B. (2008). Executive dysfunction and cognitive impairment in a large community-based sample with Multiple Sclerosis from New Zealand: A descriptive study. Archives of Clinical Neuropsychology, 23(1), 1-19.en_NZ
dc.identifier.doi10.1016/j.acn.2007.09.005en_NZ
dc.identifier.urihttps://hdl.handle.net/10289/8204
dc.language.isoenen_NZ
dc.publisherElsevieren_NZ
dc.relation.isPartOfArchives of Clinical Neuropsychologyen_NZ
dc.relation.ispartofArchives of Clinical Neuropsychology
dc.relation.urihttp://www.sciencedirect.com/science/article/pii/S088761770700203Xen_NZ
dc.subjectmultiple sclerosisen_NZ
dc.subjectexecutive functioningen_NZ
dc.subjectcognitive abilityen_NZ
dc.subjectdepressionen_NZ
dc.subjectintelligenceen_NZ
dc.subjectmemoryen_NZ
dc.titleExecutive dysfunction and cognitive impairment in a large community-based sample with Multiple Sclerosis from New Zealand: A descriptive studyen_NZ
dc.typeJournal Articleen_NZ
pubs.begin-page1en_NZ
pubs.elements-id32794
pubs.end-page19en_NZ
pubs.issue1en_NZ
pubs.volume23en_NZ
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